Waldenstrom’s Macroglobulinemia treated with fractionated low-dose total body irradiation
نویسنده
چکیده
Case Report: A 78-year-old male with relapsed Waldenstrom’s macroglobulinemia following therapy with chlorambucil underwent a five-week course of TBI. The total dose delivered was 1.5 Gy, given as 0.15 Gy twice weekly for ten sessions. During the course of therapy his CD4 cells increased from 637 (cells/mm3) to 808 partly through treatment and then declined to 654 at the completion of therapy. The CD4:CD8 ratio increased from 1.3 at the start to 1.7 at completion of therapy. His IgM levels declined from 4040 to 1640 following treatment and he became symptom-free. Other than transient thrombocytopenia, no acute or late side effects were noted.
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